A Textbook of Modern Toxicology (3rd Edition) by Ernest Hodgson

By Ernest Hodgson

Toxicology is the technology of toxins, embracing the actual and chemical learn of the entire identified toxic components, in addition to the tools of checking out for them, their motion at the dwelling physique, and the postmortem effects they party. The 3rd variation of this benchmark textual content once more proves the main authoritative source at the topic for either scholars and training execs.

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Extra info for A Textbook of Modern Toxicology (3rd Edition)

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1. Longer term assessments of cell toxicity are highly dependent on the relevant toxic end point. They may include measurement of growth competence, apoptosis, and/or necrosis, incorporation of radioactive precursors into essential cellular constituents such as RNA, DNA, and protein and specialized cellular functions. 1. 3 MOLECULAR TECHNIQUES Recombinant DNA techniques, including molecular cloning, have provided recent dramatic advances in many areas of both fundamental and applied biology, toxicology not excepted.

Immunoaffinity purification involves the use of antibodies, bound to an insoluble matrix, for chromatography. The advantage of this method is that it is highly specific, often permitting purification in a single step. Immunoprecipitation is a variant of immunoaffinity purification and is a means to remove a protein from a complex mixture in a highly specific manner. 4 The generation of antibodies of several clonal origins (polyclonal antibodies) with antibodies from each clonal origin (monoclonal antibodies A, B and C) recognizing a distinct epitope on the antigen.

Chelsea, MI: Lewis Publishers, 1991. Quality Assurance Garfield, F. M. Quality Assurance Principles for Analytical Laboratories. Arlington, VA: AOAC, 1984. (An excellent volume containing all phases of QA, including forms, equipment, and audits) Taylor, J. K. Quality Assurance of Chemical Measurements. Chelsea, MI: Lewis Publishers, 1987. (Excellent summary of principles and extensive bibliography) Analytical Methods 1. University Libraries (many scientific journals contain pesticide residue studies and can be searched through databases available on computer) a.

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