Acinetobacter Biology and Pathogenesis by Eugénie Bergogne-Bérézin (auth.), Mauro Bendinelli, Herman

By Eugénie Bergogne-Bérézin (auth.), Mauro Bendinelli, Herman Friedman, Eugénie Bergogne-Bérézin (eds.)

There is at present expanding curiosity in regards to the biology and sickness because of Acinetobacter species. Such curiosity, despite the fact that, built quite slowly a result of necessity to explain the complicated taxonomy of those organisms. a lot paintings was once had to establish a number of species as participants of this genus, to acknowledge their epidemiologic profile, their pathogenic position and their expanding significance as multi-antibiotic resistant organisms. lately development of genetic techniques, reputation of plasmids, integrons and chromosomal resources of resistance mechanisms aroused curiosity at the position of Acinetobacters in disorder through many microbiologists and clinicians, specially internists and infectious affliction experts. during this regard, physicians are often faced with tremendous tough healing techniques for therapy and prevention of critical nosocomial infections as a result of multi antibiotic resistant Acinetobacter. furthermore, contemporary observations of group received infections were suggested, in particular in sufferers with quite a few chance components reminiscent of immuno-deficiencies. additionally, it truly is now changing into obvious that Acinetobacter infections take place usually in violent occasions comparable to earthquake or struggle zones.

The mechanisms of Acinetobacter virulence have gotten more and more transparent, supplying new insights into their pathogenic position in neighborhood got infections. it truly is obvious the time is acceptable for certain assessment of the expanding wisdom relating vital new info, either medical and healing, in particular details bearing on virulence, resistance mechanisms and typing of Acinetobacter spp. Many new findings are collecting in nearly an exponential demeanour on account that book of past books in this topic in 1991 and 1996.

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The Approved Lists of Bacterial Names of 1980 included two names, A. calcoaceticus for strains forming acid from sugars and A. , 1980). , 1968) was mentioned to be generally consistent with J. , 1970). However, it was not before 1986 that 22 H. Seifert, L. Dijkshoorn 12 DNA-DNA hybridization groups (‘‘genomospecies’’, genomic species, gen. , 1991). An independent study described three additional DNA-hybridization groups, designated 13–15 (Tjernberg and Ursing, 1989). Another, concurrent DNADNA hybridization study revealed the existence of five proteolytic genomic species, numbered 13–17 (Bouvet and Jeanjean, 1989).

1979) and McDonald et al. (1999) and attributed to increased humidity in the summer months. Although various Acinetobacter species have been isolated from animals, and A. , 2000), the normal flora of animals has never been studied systematically for the presence of acinetobacters. Of note, A. baumannii was recovered from 22% of body lice sampled from homeless people (La Scola and Raoult, 2004). It has been speculated that this finding might result from clinically silent bacteremia in these people; the clinical implication of this observation, however, is not yet clear.

J Antimicrob Chemother 42: 793–802. , and Gray P. 2005. Multi-drug resistant Acinetobacte extremity infections in soldiers. Emerg Ingect Dis 11: 1218–1224. G. 1939. Organisms invalidating the diagnosis of gonorrhea by the smear method. J Bacteriol 38: 119 Dijkshoorn L. 1996. Acinetobacter – microbiology. J. ) Acinetobacter – Microbiology, Epidemiology, Infection, Management. CRC Press, New-York, Chap. 3, pp. 37–69 Dijkshoorn L. 2006. Two decades experience of typing Acinetobacter strains: evolving methods and clinical application.

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