Advances in Spinal Fusion: Molecular Science, BioMechanics, by Kai-Uwe Lewandrowski

By Kai-Uwe Lewandrowski

Advances in Spinal Fusion unearths a brand new new release of fabrics and units for improved operations in spinal fusion. This reference showcases rising learn and applied sciences in components reminiscent of biodegradable implants, drug supply, stem cellphone isolation and transfection, phone encapsulation and immobilization, and the layout of 2nd and 3D scaffolds for cells. It captures a cascade of techniques the most important to elevated therapeutic and reduced morbidity in spinal fusion tools and mechanics and addresses present criteria in analytical technique and quality controls, it describes the choice of biomaterials for stronger biocompatibility, biostability, and structure/function relationships.

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Med 2002; 13:1–5. 63. Cotten A, Boutry N, Cortet B, Assaker R, Demondion X, Leblond D, Chastanet P, Duquesnoy B, Deramond H. Percutaneous vertebroplasty: state of the art. Radiographics 1998; 18:311–323. 64. Deramond H, Depriester C, Toussaint P, Galibert P. Percutaneous vertebroplasty. Semin. Musculoskelet. Radiol 1997; 1:285–295. 65. Jasper LE, Deramond H, Mathis JM, Belkoff SM. The effect of monomer-to-powder ratio on the material properties of Cranioplastic. Bone 1999; 25:27S–29S. 66. Belkoff SM, Sanders JC.

48. Liebschner MAK, Rosenberg WS, Keaveny TM. Effects of bone cement volume and distribution on vertebral stiffness after vertebroplasty. Spine 2001; 26:1547–1554. 49. Terjesen T, Apalset K. The influence of different degrees of stiffness of fixation plates on experimental bone healing. J. Orthop. Res 1988; 6:293–299. 50. Jensen ME, Kallmes DF, Short JG, Schweikert PJ, Marx WF. Percutaneous vertebroplasty does not increase the risk of adjacent vertebral fracture—a retrospective study. Presented at the 38th Annual Meeting of the American Society of Neuroradiology, Atlanta, GA, April 3, 2000.

This is corroborated by clinical evidence, demonstrating 99% and 92% of predicted anterior and middle VB dimensions, respectively, when kyphoplasty is performed less than 3 months after fracture [1]. Some surgeons claim that vertebroplasty can restore some VB height, although this has not been demonstrated in a clinical trial [21]. V. INDICATIONS A. Kyphoplasty 1. As a Pain-Relieving Procedure A major complaint of patients with osteoporotic VCFs is pain. This pain can become progressive and intractable, affecting the patient’s ability to perform his or her daily activities.

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